Preparation of olefinic compounds and intermediates thereof

Organic compounds -- part of the class 532-570 series – Organic compounds – Silicon containing

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560 53, 560 57, 560 60, 560174, 560177, 560183, 546267, 546268, 546341, 546342, C07B 4106, C07C 69738, C07C 69732, C07C 67313

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046508902

ABSTRACT:
7-Substituted lower alkyl hept-6-enoates and 4-hydroxy-tetrahydropyran-2-ones bearing 6-olefinic substituents (E), (Z), ethyl erythro-3,5-dihydroxy-7-phenyl-hept-6-enates are prepared by a multi-step process involving lower alkyl 3,5-dihydroxy-hept-6-enates. The final products are useful as anti hypercholesteremic agents.

REFERENCES:
patent: 4277610 (1981-07-01), Cohen et al.
Streitwieser, et al "Introduction to Organic Chemistry" (1976) pp. 381-383, 394, 395.

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