Preparation of N,N'-dicarboxymethyl-1,3-propanediamines

Details Preparation of N,N'-dicarboxymethyl-1,3-propanediamines Preparation of N,N'-dicarboxymethyl-1,3-propanediamines

1975-11-11

1976-10-26

Gotts, Lewis

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

260251R, 2604381, 260439R, 260519, C07C10102

Patent

active

039883671

ABSTRACT:
N,N'-Dicarboxymethyl-1,3-propanediamine (designated PDDA) is prepared by reacting 1,3-propanediamine with formaldehyde and HCN to form hexahydropyrimidine-1,3-diacetonitrile, which is hydrolyzed with an aqueous alkali metal hydroxide to form dialkali metal hexahydropyrimidine-1,3-diacetate which, in turn, is reacted with mineral acid to form the desired PDDA and formaldehyde.
N,n'-dicarboxymethyl-2-hydroxy-1,3-propanediamine (designated HYDROXY-PDDA) is prepared by reacting 1,3-diamino-2-propanol with formaldehyde and HCN to form 5-hydroxyhexahydropyrimidine-1,3-diacetonitrile, which is hydrolyzed with an aqueous alkali metal hydroxide to form dialkali metal 5-hydroxyhexahydropyrimidine-1,3-diacetate which, in turn, is reacted with acid to form the desired HYDROXY-PDDA and formaldehyde.

REFERENCES:
patent: 2413856 (1947-01-01), Bersworth
patent: 2558923 (1951-07-01), Bersworth
patent: 3689544 (1972-09-01), Scanlon et al.
patent: 3872120 (1975-03-01), Mod et al.
Johnson et al., J. Org. Chem., vol. 27, 2077-2080, (1962).

Affiliated with

Also associated with

Rating

Preparation of N,N'-dicarboxymethyl-1,3-propanediamines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of N,N'-dicarboxymethyl-1,3-propanediamines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of N,N'-dicarboxymethyl-1,3-propanediamines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-184722