Preparation of N-formyl-L-aspartic anhydride

Details Preparation of N-formyl-L-aspartic anhydride Preparation of N-formyl-L-aspartic anhydride

1989-11-28

1990-07-31

Killos, Paul J.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

562898, C07D30722

Patent

active

049451723

ABSTRACT:
N-formyl-L-aspartic anhydride is prepared using a minimum excess of formic acid. Acetic anhydride and a C.sub.3 -C.sub.6 secondary alcohol are added to the reaction mixture to consume excess formic acid. The reaction is suitable for further reactions without modification.

REFERENCES:
patent: 3816471 (1974-06-01), Ariyoshi et al.
patent: 4526985 (1985-07-01), Giobbio et al.
patent: 4550180 (1985-10-01), Takemoto et al.
patent: 4810816 (1989-03-01), Tsuji et al.

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