Preparation of N-alkylpiperazines

Details Preparation of N-alkylpiperazines Preparation of N-alkylpiperazines

1993-07-07

1995-05-09

Bernhardt, Emily

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

5483001, C07D29503

Patent

active

054140870

ABSTRACT:
Disclosed is a one-step method for preparing N-alkylpiperazines which eliminates the initial preparation and isolation of piperazine which comprises reacting a carbonyl compound and an amine in the presence of hydrogen over a metallic hydrogenation-dehydrogenation catalyst from Group VIII of the Periodic Table such as, for example, nickel, copper, cobalt, chromium, palladium, platinum or ruthenium, alone or in combination with other Group VIII metals or transition metals selected from the group consisting of manganese, iron, zinc, copper and chromium.

REFERENCES:
patent: 3152998 (1964-10-01), Moss
patent: 3607874 (1971-09-01), Fuerst
patent: 3654370 (1972-04-01), Yeakey
patent: 3948900 (1976-04-01), Moss
patent: 4757144 (1988-07-01), Okabe et al.

Affiliated with

Also associated with

Rating

Preparation of N-alkylpiperazines does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of N-alkylpiperazines, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of N-alkylpiperazines will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1706362