Preparation of N-(2-alkoxyethyl)alkanamides and 2-alkoxyethyl am

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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260307F, 260584C, C07C10200, C07C 8500

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active

040241840

ABSTRACT:
N-(2-alkoxyethyl)alkanamides, such as N-(2-ethoxyethyl)ethanamide and N-(2-methoxyethyl)propanamide, are prepared by reacting a 2-oxazoline with methanol or ethanol in the presence of a strong base, such as sodium methoxide. Subsequent hydrolysis of such amides provides a convenient means for obtaining 2-alkoxyethyl amines.

REFERENCES:
patent: 2048821 (1936-07-01), Schneider
patent: 2416552 (1947-02-01), Valku
Krabbe et al., Chem. Bencht., 73 (1940), pp. 657-661.
Frump, Chemical Reviews, 71 (1971), pp. 494-495, 497-498.

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