Chemistry: molecular biology and microbiology – Micro-organism – tissue cell culture or enzyme using process... – Preparing heterocyclic carbon compound having only o – n – s,...
Patent
1980-04-04
1982-04-06
Tanenholtz, Alvin E.
Chemistry: molecular biology and microbiology
Micro-organism, tissue cell culture or enzyme using process...
Preparing heterocyclic carbon compound having only o, n, s,...
435911, 2603435, 424279, C12P 1706
Patent
active
043236480
ABSTRACT:
Monacolin K, which is an antihypercholesteraemic agent of molecular formula C.sub.24 H.sub.36 O.sub.5, is prepared by cultivating one or more of the microorganisms Monascus anka SANK 10171 (IFO 6540), Monascus purpureus SANK 10271 (IFO 4513), Monascus ruber SANK 10671 (FERM 4958), Monascus vitreus SANK 10960 (FERM 4960), Monascus paxii SANK 11172 (IFO 8201), Monascus ruber SANK 13778 (FERM 4959), Monascus ruber SANK 15177 (FERM 4956) or Monascus ruber SANK 18174 (FERM 4957) in a suitable culture medium and then isolating the Monacolin K from the resulting culture broth.
REFERENCES:
Journal of the Chemical Society (London), pp. 4579-4584, (1961).
Tetrahedron Letters No. 5, pp. 24-27, (1960).
Furuya Kouhei
Iwado Seigo
Kuroda Masao
Tanzawa Kazuhiko
Tsujita Yoshio
Sankyo Company Limited
Tanenholtz Alvin E.
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