Preparation of iodixanol

Details Preparation of iodixanol Preparation of iodixanol

2005-12-13

2005-12-13

Kumar, Shailendra (Department: 1621)

Organic compounds -- part of the class 532-570 series

Organic compounds

Amino nitrogen containing

C424S009452

Reexamination Certificate

active

06974882

ABSTRACT:
A process for the preparation of iodixanol by dimerization of 5-acetamido-N,N′-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-isophthalamide (“Compound A”) in which, after the dimerization step, unreacted Compound A is precipitated from the reaction mixture and recovered for re-use. The process substantially increases the net yield of iodixanol and simplifies its purification.

REFERENCES:
patent: 3816521 (1974-06-01), Ueno et al.
patent: 5235116 (1993-08-01), Fuller, Jr.
patent: 5349085 (1994-09-01), Hansen et al.
patent: 0 108 638 (1984-05-01), None
patent: 0 108 638 (1986-07-01), None
patent: WO 98/08805 (1998-03-01), None
patent: 98/23296 (1998-06-01), None

Affiliated with

Also associated with

Rating

Preparation of iodixanol does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of iodixanol, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of iodixanol will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-3490361