Preparation of indole derivatives

Details Preparation of indole derivatives Preparation of indole derivatives

1991-06-20

1992-04-07

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548508, C07D20916, C07D20904

Patent

active

051030209

ABSTRACT:
A method for the preparation of 3-(2-aminoethyl)-N-methyl-1H-indole-5-methanesulphonamide by reaction of 4-hydrazino-N-methylbenzenemethanesulphonamide and 4-chloro-1-hydroxybutanesulphonic acid, sodium salt in the presence of an acid.

REFERENCES:
patent: 4816470 (1989-03-01), Dowle et al.
patent: 4870096 (1989-09-01), Oxford et al.
patent: 5037845 (1991-08-01), Oxford
Grandberg et al., Khim. Geterotsikl. Soedin., 1974, Nr. 8, 1085 (translation).
CA 100:103175y Heterocyclic Compounds and Pharmaceuticals, Dowle et al., pp. 634-635, 1982.
CA 105:78831c 3-[2-(Dimethylamino)ethyl]-N-methyl-1H-indole-5-methanesulfonamide, Oxford, p. 637, 1984.

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