Drug – bio-affecting and body treating compositions – Lymphokine
Patent
1990-01-10
1992-04-21
Brown, Johnnie R.
Drug, bio-affecting and body treating compositions
Lymphokine
424 90, 435236, 435238, 546270, A61K 3912, C12N 704
Patent
active
051066190
ABSTRACT:
Vaccines employing inactivated viruses having improved retention of antigenic characteristics are prepared by psoralen-inactivation of the live virus in a non-oxidizing atmosphere. By excluding oxygen and other oxidizing species from the inactivation medium, degradation of the antigen characteristics resulting from irradiation with ultraviolet light is largely prevented. The resulting inactivated viruses are employed in vaccine preparations for the inoculation of susceptible hosts to inhibit viral infection.
REFERENCES:
patent: 4036952 (1977-07-01), Bauer et al.
Creagan Richard P.
Giles Richard
Stevens David R.
Wiesehahn Gary P.
Brown Johnnie R.
Diamond Scientific Co.
Gil Joseph C.
Mohamed Abdel A.
Whalen Lyndanne M.
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