Preparation of immortalized cells

Details Preparation of immortalized cells Preparation of immortalized cells

1996-12-13

1998-11-03

Saunders, David

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving viable micro-organism

435352, 435354, 435377, 435384, C12N 506, C12Q 102

Patent

active

058306820

ABSTRACT:
All lines have been prepared from growth suppressor gene deficient animals. The cells include immortalized precursor cells and differentiated cells such as osteoclast precursors, osteoblast precursors, megakaryocytes, osteoclasts, osteoblasts, pancreatic .alpha.-cells, pancreatic .beta.-cells, pancreatic .delta.-cells, adipocytes, macrophages, chondrocytes, dendritic cells, hepatocytes, myocytes and prostatic cells. The cells are useful for constructing cDNA and protein libraries, screening agonists and antagonists of compounds and factors that affect metabolic pathways of specific cells and generating cell-specific antibodies.

REFERENCES:
patent: 5683906 (1997-11-01), Moore
Thompson, DL et al. J. Bone and Mineral Res. 11(supp. 1): S108. abstract #54, Aug. 1996.

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