Preparation of imidazole-2-carboxylic acids

Details Preparation of imidazole-2-carboxylic acids Preparation of imidazole-2-carboxylic acids

1989-02-10

1992-05-26

Richter, Johann

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548331, 548337, 548343, C07D23530, C07D43530

Patent

active

051170043

ABSTRACT:
4,5-Disubstituted imidazole-2-carboxylic acids are prepared by reacting 4,5-disubstituted imidazoles with carbon dioxide under superatmospheric pressure at from 150.degree. to 300.degree. C. in the presence of a base.

REFERENCES:
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patent: 4369186 (1983-01-01), Beck et al.
patent: 4672128 (1987-06-01), Kemp et al.
Journal of the Chemical Society, vol. CXV., pp. 217-260 (1919).
A. Bistrzycki, et al., Chem. Ber. 45 (1912), 3483.
J. Dirlam et al., J. Heterocycl. Chem. 17 (1980), 409-411.
B. Iddon, et al., Tetrahedron Letters 27 (1986), 1635-1638.
S. Roseman, J. Amer. Chem. Soc. 75 (1953) 3854.

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