Preparation of hydroxyalkylpiperazinones by reacting a 2,3-dihyd

Details Preparation of hydroxyalkylpiperazinones by reacting a 2,3-dihyd Preparation of hydroxyalkylpiperazinones by reacting a 2,3-dihyd

1988-12-05

1989-11-14

Hollrah, Glennon H.

Organic compounds -- part of the class 532-570 series

Organic compounds

Nitrogen attached directly or indirectly to the purine ring...

540492, C07D24108

Patent

active

048809349

ABSTRACT:
A process for the preparation of 4-(2-hydroxyalkyl)-2-piperazinones and their substituted derivatives comprising reacting an N-hydroxyalkylalkylenediamine, e.g. 2-[(2-aminoethyl)amino]ethanol, or a hydrocarbyl substituted derivative thereof with an .alpha.,.beta.-dicarbonyl compound, e.g. glyoxal, an alkyl-substituted derivative of glyoxal or a glyoxal equivalent. Certain hexahydro-4-(hydroxyalkyl)-2H-1,4-diazepin-2-ones have been made which are new compounds.

REFERENCES:
patent: 4767860 (1988-08-01), Dunmore et al.

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