Preparation of highly hydrated self-supporting hyaluronic acid c

Details Preparation of highly hydrated self-supporting hyaluronic acid c Preparation of highly hydrated self-supporting hyaluronic acid c

1995-06-07

1997-04-08

Webman, Edward J.

Drug, bio-affecting and body treating compositions

Preparations characterized by special physical form

Matrices

264186, 26417718, A61K 970, D01F 904

Patent

active

056185618

ABSTRACT:
This invention provides new gels in the form of highly hydrated self-supporting film, comprising one or more alkaline alginates, an alkaline earth alginate, a polyalcohol and a hyaluronic acid or a derivative thereof, and their preparation process. These polysaccharide-matrix gels in highly hydrated self-supporting film form are suitable for use as covering and protection materials for cutaneous lesions and/or pathologies in that they are obtainable in self-supporting form in the desired thickness, are transparent, flexible, have good mechanical characteristics, are adaptable to the lesion surface without strongly adhering to it, and are permeable to gas but are impermeable to liquids and bacteria; one or more pharmacologically active substances can also be incorporated in the gel.

REFERENCES:
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patent: 4443538 (1984-04-01), Cheetham
patent: 4524064 (1985-06-01), Nambu
patent: 4554166 (1985-11-01), Morimoto
patent: 4844902 (1989-07-01), Grohe
patent: 4948575 (1990-08-01), Cole et al.
patent: 5071741 (1991-12-01), Brockbank
patent: 5194253 (1993-03-01), Garrido

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