Preparation of heterocycles using 1,3-dihalopropenes

Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...

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546251, 546330, 546336, 546345, 544180, C07D21306, C07D21308, C07D21309

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059327367

ABSTRACT:
Described are preferred processes for preparing heterocycles having one or more nitrogen and/or oxygen heteroatoms, utilizing a 1,3-dihalopropene as an effective 3-carbon fragment. Preferred processes yield pyridines, quinolines, oxazoles, pyrimidines and pyrazoles, depending upon the other reactant or reactants utilized with the 1,3-dihalopropene.

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K. Schulze, F. Richter, R. Weisheit, R. Krause, M. Muhlstadt, M. Muhlstadt, "Zur Darstellung und Charakterisierung von Vinylsenfolen", Journal F. prakt. Chemie, Band 322, Heft 4, 1980, S. 629-637 (1980).
A.K. Mukerjee and R. Ashare, "Isothiocyanates in the Chemistry of Heterocycles", Chemical Reviews, vol. 91, No. 1, pp. 1-24 (Jan./Feb. 1991) .

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