Preparation of herpes simplex antigen for the diagnosis of carci

Chemistry: molecular biology and microbiology – Virus or bacteriophage – except for viral vector or... – Recovery or purification

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260112R, 424 86, 424 89, 424177, 424180, 435 1, 435 5, 435 7, 435 68, 435235, 435241, 435803, 436543, 436813, C12N 102, C12N 702, C12Q 100

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043919111

ABSTRACT:
The invention relates to a process for the industrial production of a product for the diagnosis of carcinoma consisting of an antigen obtained by the infection with Herpes Simplex Virus of cells of guinea-pig kidney, the process comprising three main sections, in the first of which the antigen is produced, in the second section a biochemical purification of the antigen is carried out, while in the third section the product is prepared in preservable condition and confection.

REFERENCES:
Tarro, Tumori, vol. 62, 1976, pp. 615-622.
Hollinshead, Viral Immunodiagnosis, Acd. Press, N.Y., 1974, pp. 301-317.
Hollinshead, Cancer Res., vol. 34, 1974, pp. 1122-1125.
Tarro, Tumori, vol. 62, 1976, pp. 609-614.
Shillitoe, Oncology, vol. 33, 1976, pp. 192-195.
Tarro, Oncogineses & Herpesvirases II, reprint pp. 291-297, (IARC Sci. Pub. No. 11), 1975.
Tarro, Chem. Abs., vol. 78, 1973, AB No. 156304y, & AB No. 109227r.
Tarro, Chem. Abs., vol. 81, 1974, AB No. 134459n.
Tarro, Chem. Abs., vol. 92, 1980, AB No. 178870w, citing Cell Mol. Biol., 1979, 25(5), pp. 329-33.
Kaplan, The Herpes Virus, Acad. Press, New York, 1973, pp. 97-110, 178-184.

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