Organic compounds -- part of the class 532-570 series – Organic compounds – Heterocyclic carbon compounds containing a hetero ring...
Patent
1983-03-24
1984-05-29
Chan, Nicky
Organic compounds -- part of the class 532-570 series
Organic compounds
Heterocyclic carbon compounds containing a hetero ring...
C07D30922
Patent
active
044516614
ABSTRACT:
A process for preparing a compound of the formula: ##STR1## wherein R is hydrogen, lower alkyl of 1 to 6 carbon atoms, lower alkenyl of 2 to 6 carbon atoms, phenyl or benzyl; and R' is lower alkyl of 1 to 6 carbon atoms which comprises contacting a compound of the formula ##STR2## wherein R and R' are defined as above at -10.degree. to 50.degree. C. with an essentially anhydrous acid selected from the group consisting of formic acid, trifluoroacetic acid, p-toluenesulfonic acid, methanesulfonic acid, citric acid, oxalic acid, chloroacetic acid, sulfuric acid, hydrochloric acid, phosphoric acid and hydrofluoric acid.
REFERENCES:
patent: 3707482 (1972-12-01), Laliberte
patent: 3751434 (1973-08-01), Lefebvre
patent: 4059595 (1977-11-01), Shono et al.
Laliberte et al., J. Med. Chem. 16, pp. 1084-1089 (1973).
Achmatowicz et al., Tetrahedron 32, pp. 1051-1054 (1976).
Achmatowicz, Jr. et al., Tetrahedron, vol. 27, 1971, pp. 1973-1996.
Allingham Robert P.
Weeks Paul D.
Chan Nicky
Pfizer Inc.
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