Preparation of fibroblast-populated connective tissue...

Chemistry: molecular biology and microbiology – Animal cell – per se ; composition thereof; process of... – Primate cell – per se

Reexamination Certificate

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C435S373000, C435S382000, C435S393000

Reexamination Certificate

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07816133

ABSTRACT:
Disclosed is a method for in vitro growing of connective tissue substitute, said connective tissue substitute being populated with fibroblasts, a connective tissue substitute obtainable by such a method, as well as a method for closing of a wound, wherein such connective tissue substitute is applied onto a wound.

REFERENCES:
patent: 6846675 (2005-01-01), Conrad et al.
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Lee Dong-Youn et al: “A new skin equivalent model: Dermal substrate that combines de-epidermized dermis with fibroblast-populated collagen matrix” Journal of Dermatological Science, vol. 23, No. 2, Jun. 2000, pp. 132-137, XP002301200 ISSN: 0923-1811 cited in the application the whole document.
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Krejci N C et al: “In-vitro reconstitution of skin: Fibroblasts facilitate keratinocyte growth and differentiation on acellular reticular dermis” Journal of Investigative Dermatology, vol. 97, No. 5, Nov. 1991, pp. 843-848, XP008037008 ISSN: 0022-202X the whole document.

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