Preparation of factor XIIIa by gene manipulation

Details Preparation of factor XIIIa by gene manipulation Preparation of factor XIIIa by gene manipulation

2007-05-22

2007-05-22

Kemmerer, Elizabeth C. (Department: 1646)

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Recombinant dna technique included in method of making a...

C435S320100, C435S325000, C435S358000, C435S252300, C435S254110, C435S254210, C536S023100, C536S023200, C536S023500

Reexamination Certificate

active

08459044

ABSTRACT:
The cDNA which codes for factor XIIIa has been isolated using a cDNA bank from human placenta and probes constructed on the basis of the amino acid sequence of factor XIIIa peptide fragments. It is possible with this cDNA not only to obtain factor XIIIa by gene manipulation in high purity but also to prepare diagnostic aids which permit the analysis of genetic factor XIIIa defects. Furthermore, it is possible on the basis of the amino acid sequence to prepare antibodies which are suitable for diagnostic aids and antibody columns.

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