Preparation of enriched whole virus radioligand

Details Preparation of enriched whole virus radioligand Preparation of enriched whole virus radioligand

1979-09-13

1981-08-04

Wiseman, Thomas G.

Chemistry: molecular biology and microbiology

Measuring or testing process involving enzymes or...

Involving virus or bacteriophage

435 7, 435177, 435188, 435235, 435236, 435239, 424 15, 424 12, 23230B, C12N 700, C12N 702, G01N 3354, G01N 3300

Patent

active

042823153

ABSTRACT:
Obtaining a virus subpopulation, useful in qualitative and quantitative biological assay procedures, of enhanced sensitivity toward host cells for the virus by contacting a virus population with an inanimate substrate having moieties which mimic host cell receptor sites for cell binding protein of the virus and recovering as said subpopulation the portion of the initial virus population which complexes with the substrate.

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patent: 4176174 (1979-11-01), Russell et al.
patent: 4178360 (1979-12-01), Cleeland et al.
patent: 4195074 (1980-03-01), Safford
McDonald et al., "Preparation and Characterization of an .sup.125 T-Labeled Sendai Virus Ligand", Anal. Biochem. vol. 106, (1980), pp. 127-133.
Baird et al., "Evidence That MuLV-Induced Thymic Lymphoma Cells Possess Specific Cell Membrane Binding Sites For MuLV", Int. J. Cancer, vol. 19, (1977), pp. 403-413.
Fowler et al., "Binding Characteristics of Rauscher Leukemia Virus Envelope Glycoprotein gp 71 to Murine Lymphoid Cells", J. Vir. vol. 24, No. 3 (1977), pp. 729-735.
Greaves, "Virus `Receptors` on Lymphocytes", Scand. J. Immunol., vol. 5, Suppl. 5, (1976), pp. 113-123.
Scheid et al., "Activation of Cell Fusion and Infectivity by Proteolytic Cleavage of a Sendai Virus Glycoprotein", Proteuses and Biological Control, Cold Spring Harbor Laboratory, (1975), pp. 645-659.
Shuurs et al., "Enzyme-Immunoassay", Clin. Chim. Acta, vol. 81, No. 1 (1977), pp. 1-40.
Fenner et al., Medical Virology, Academic Press, NY, (1970), pp. 45-46.
Baum et al., "Affinity Chromatography", Immobilized Enzymes, Antigens, Antibodies, and Peptides, Weetall ed., Marcel Dekker, Inc., NY, pp. 419-425, 451-454.

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