Preparation of electrolyte solutions and containers containing s

Drug – bio-affecting and body treating compositions – Inorganic active ingredient containing – Elemental chlorine or elemental chlorine releasing inorganic...

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Details

424665, 424678, 424679, 424680, 424681, 424715, 424717, 604 7, 604403, 604411, A61K 3314

Patent

active

052002004

ABSTRACT:
Methods are provided for preparing just before administration unit doses of therapeutic solutions which contain redox active unstable and/or diffusable metabolites such as a ketoacid, a sulfhydryl-contining amino acid, or carbon dioxide. The method involves preparing and storing an aqueous solution of stable components which may or may not contain carbon dioxide. A dry powder comprised of unstable components is also prepared and stored separately. These separate component compositions are packaged in, for example, individual chambers of a common scaled container which is so constructed as to permit the opening, by externally applied manual means or the like, of a passageway between such chambers at the time when usage is contemplated. Thus, a fresh solution in desired full dosage form is preparable just befor administration. Improved container structures for practice of this method are also provided.

REFERENCES:
patent: 3978212 (1976-08-01), Barna
patent: 4489535 (1984-12-01), Veltman
patent: 4609372 (1986-09-01), Carmen et al.

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