Preparation of directly iodinated steroid hormones and related c

Details Preparation of directly iodinated steroid hormones and related c Preparation of directly iodinated steroid hormones and related c

1976-09-27

1982-03-23

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603974, 2603975, 26039745, C07J 500, C07J 100

Patent

active

043212085

ABSTRACT:
A process for the direct iodination of steroids and steroid hormones in the presence of hydrogen peroxide or chloramine-T is disclosed. The antigenicity and the specific receptor binding of directly iodinated estradiol 17-beta is identical to tritiated estradiol 17-beta.

REFERENCES:
patent: 3933869 (1976-01-01), Schulze
patent: 3953431 (1976-04-01), Rutner et al.
patent: 3954739 (1976-03-01), Wilkinson
patent: 4013688 (1977-03-01), Babcock et al.
Chem. Abstracts, vol. 83 (1975), Par 190024y.

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