Preparation of cyanoacetamide and 2,2-dibromo-3-nitrilopropionam

Details Preparation of cyanoacetamide and 2,2-dibromo-3-nitrilopropionam Preparation of cyanoacetamide and 2,2-dibromo-3-nitrilopropionam

1979-11-26

1982-05-04

Brust, Joseph Paul

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

424304, C07C121417, C07C12000, A01N 3718, A01N 3734

Patent

active

043281710

ABSTRACT:
An alkyl .alpha.-cyanoacetate is reacted with ammonia in a glycol solvent medium to form cyanoacetamide. Advantageously and without requirement of separation of the formed cyanoacetamide in glycol solvent (even though the next step and entire procedure can optionally commence with pre-formed cyanoacetamide), 2,2-dibromo-3-nitrilopropionamide is formed in situ by treating the cyanoacetamide in glycol with an appropriate mixture of bromine and an alkali metal bromate at about 10.degree. C-40.degree. C. Excellent and stable antimicrobial compositions may then be prepared, as part of an overall integrated process by incorporating in the resultant 2,2-dibromo-3-nitrilopropionamide-containing reaction mass an appropriate quantity of paraformaldehyde or equivalent satisfactory stabilizer at a suitably adjusted pH level.

REFERENCES:
patent: Re29826 (1978-11-01), Konya et al.
patent: 2419888 (1947-04-01), Nolan et al.
patent: 3403174 (1968-09-01), Chance et al.
patent: 3488734 (1970-01-01), Burk
patent: 3493658 (1970-02-01), Schmidt et al.
patent: 3557184 (1971-01-01), Toepfl et al.
patent: 3647610 (1972-03-01), Wolf
patent: 3649166 (1972-03-01), Wolf et al.
patent: 3668231 (1972-06-01), Rosin et al.
patent: 3689660 (1972-09-01), Burk et al.
patent: 3733332 (1973-05-01), Toepfl et al.
patent: 3751444 (1973-08-01), Solem et al.
patent: 3839583 (1974-10-01), Shema et al.
patent: 3864253 (1975-02-01), Shema et al.
patent: 3865724 (1975-02-01), Shema et al.
patent: 3873444 (1975-03-01), Shema et al.
patent: 3896231 (1975-07-01), Shema et al.
patent: 3897554 (1975-07-01), Shema et al.
patent: 3897562 (1975-07-01), Shema et al.
patent: 3915685 (1975-10-01), Konya et al.
patent: 3928198 (1975-12-01), Brink, Jr. et al.
patent: 3928575 (1975-12-01), Moyle et al.
patent: 3929562 (1975-12-01), Shema et al.
patent: 3930015 (1975-12-01), Swered et al.
patent: 3932476 (1976-01-01), Bergeron
patent: 4022605 (1972-05-01), Konya et al.
patent: 4163796 (1979-08-01), Burk
C.A., 84:100855k, (1976).
Beilstein's Handbuch; Mainwork, vol. 2, pp. 595-596; Suppl. II, vol. 2, p. 539; Suppl. III, vol. 2, p. 1641.
Beilstein's Handbuch; MainWork, vol. 2, p. 589; Suppl. I, vol. 2, p. 256; Suppl. II vol. 2, pp. 534-535; Suppl. III, vol. 2, pp. 1632-1633; Suppl. IV, vol. 2, pp. 1891-1892.
C.A. 23:2151q, (1929).
C.A., 89:146396t, (1978).
C.A., 65:2216f, (1966).
C.A., 77:156334n, (1972).
C.A., 89:179553v, (1978).
C.A., 83:109779a, (1975).

Affiliated with

Also associated with

Rating

Preparation of cyanoacetamide and 2,2-dibromo-3-nitrilopropionam does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of cyanoacetamide and 2,2-dibromo-3-nitrilopropionam, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of cyanoacetamide and 2,2-dibromo-3-nitrilopropionam will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-881238