Preparation of corticoids from 17-keto steroids

Details Preparation of corticoids from 17-keto steroids Preparation of corticoids from 17-keto steroids

1982-05-17

1983-11-01

Roberts, Elbert L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2602395, 2603975, C07J 700

Patent

active

044129556

ABSTRACT:
Disclosed is a 20,21-dihalo steroid (VII) and a steroidal sulfoxide (VIII) as well as processes to produce them. The 20,21-dihalo steroid (VII) and sulfoxide (VIII) are intermediates useful in the preparation of pharmaceutically useful corticoids.

REFERENCES:
patent: 4041055 (1977-08-01), Shephard et al.
patent: 4357279 (1982-11-01), Walker et al.
J. Am. Chem. Soc. 86, 3840 (1964).
J. Org. Chem. 35, 2831 (1970).

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