Preparation of continine by reacting nicotine with bromide and b

Details Preparation of continine by reacting nicotine with bromide and b Preparation of continine by reacting nicotine with bromide and b

1995-06-07

1997-04-29

Rotman, Alan L.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

5462794, C07D40104, C07D40304

Patent

active

056250703

ABSTRACT:
Cotinine is prepared from nicotine or nicotine sulfate by mixing a solution thereof with compounds having the formula XBr, YBrO.sub.3 where X is hydrogen or an alkali metal and Y is an alkali metal to produce an intermediate product: dibromocotinine hydrobromide perbromide, which is reduced and de-brominated to produce cotinine.

REFERENCES:
Biochemical Preparations, vol. 10, pp. 36-39; John Wiley & Sons, New York, 1963.
Synthetic Communications, 18(12) pp. 1331-1337 (1988).
Peeters et al., Journal of Labelled Compounds and Radiopharmaceuticals, vol. 27(5), pp. 605-611, May 1989.
Desai et al., Journal of Radiolabelled Compounds and Radiopharmaceuticals, vol. 29, (3) Mar. 1991.

Affiliated with

Also associated with

Rating

Preparation of continine by reacting nicotine with bromide and b does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of continine by reacting nicotine with bromide and b, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of continine by reacting nicotine with bromide and b will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-707081