Preparation of chlorinated paclitaxel analogues and use thereof

Details Preparation of chlorinated paclitaxel analogues and use thereof Preparation of chlorinated paclitaxel analogues and use thereof

1996-05-29

1998-12-29

Trinh, Ba K.

Drug, bio-affecting and body treating compositions

Designated organic active ingredient containing

Having -c-, wherein x is chalcogen, bonded directly to...

549510, 549511, A61K 31335, C07D30514

Patent

active

058542787

ABSTRACT:
Provided are novel paclitaxel analogues which are selectively chlorinated stereospecific derivatives of cephalomannine and 7-epi-cephalomannine having paclitaxel-like antitumor efficacy, methods for their preparation and methods for treating tumors with these compounds.

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