Preparation of carrier-bound macromolecular compounds

Textiles: fiber preparation

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195 68, 195DIG11, 260112R, C07G 702

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active

040813290

ABSTRACT:
Carrier-bound macromolecular compounds, especially bioactive macromolecular compounds, are produced by reacting a macromolecular compound A with a coupling compound B containing at least one reactive function capable of coupling with compound A and at least one further reactive function capable of polymerization, adding to the resulting coupled reaction product AB an unswollen molecular sieve material having cross-linking sufficient to exclude penetration by compound A, and polymerizing the polymerizable group of the coupled product AB in the molecular sieve material to form a polymer body in the molecular sieve material and fix compound A on the surface of the molecular sieve material. Compound A can be, e.g., an enzyme, antibody or hormone, and coupling compound B typically contains, as the coupable function, an alkylation or acylation group such as oxirane, ethyleneimine, halide, acid halide, azide or anhydride groups, and, as the polymerizable function, a carbon-carbon or carbon-oxygen double bond.

REFERENCES:
patent: 3775253 (1973-11-01), Jaworek et al.
patent: 3791927 (1974-02-01), Forgione et al.
patent: 3806417 (1974-04-01), Beaucamp et al.
patent: 3849253 (1974-11-01), Harvey et al.

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