Preparation of blood fraction

Details Preparation of blood fraction Preparation of blood fraction

1979-01-23

1980-10-21

Waddell, Frederick E.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

A61K 3514

Patent

active

042294355

ABSTRACT:
Concentrates of one of the coagulation factors II, V and VIII or a mixture thereof or blood plasma free from one or more of the coagulation factors VII, IX, X, XI and XII can be prepared by adding a reducing substance comprised of dithiothreitol, dithioerythritol, lipoic acid, mercaptoethanol, or a borohydride to blood or plasma, dithiothreitol being preferred. The amount of reducing substance and the period of time for interaction are so adapted to obtain the product desired, whereafter the blood and plasma, respectively, are optionally fractionated in a known manner.

REFERENCES:
patent: 3920625 (1975-11-01), Andersson et al.

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