Preparation of biologically active molecules by molecular imprin

Plastic and nonmetallic article shaping or treating: processes – Mechanical shaping or molding to form or reform shaped article – Shaping against forming surface

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264108, 264219, 264220, 264221, 264225, 264226, 264227, 26433111, 26433116, 26433119, 264DIG44, 424 7808, 424 7837, 5262381, 5262382, C08J 500

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active

058582967

ABSTRACT:
A method for preparing mimics of a wide variety of drugs and other biologlly active molecules using molecular imprinting techniques, and the mimics produced thereby, is disclosed. Specifically, the mimic is designed by: (i) polymerization of functional monomers around a known drug or biologically active molecule (the template) that exhibits a desired activity; (ii) removal of the template molecule; and then (iii) polymerization of a second class of monomers in the void left by the template, to provide a new organic molecule which exhibits one or more desired properties which are similar to that of the template.

REFERENCES:
patent: 4334844 (1982-06-01), Tanaka

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