Chemistry of hydrocarbon compounds – Aromatic compound synthesis – By condensation of entire cyclic molecules or entire...
Patent
1988-10-25
1990-03-27
Davis, Curtis R.
Chemistry of hydrocarbon compounds
Aromatic compound synthesis
By condensation of entire cyclic molecules or entire...
585469, 562466, C07C 202, C07C 120
Patent
active
049122762
ABSTRACT:
A method for the preparation of biaryl compounds is disclosed which comprises contacting an aryl halide under conditions suitable to form a Grignard reagent and thereafter contacting the Grignard reagent with an aryl chloride in the presence of a catalyst comprising a nickel compound and a coordinating ligand under conditions suitable for the formation of biaryl compound. In an alternate embodiment of the present invention, biaryl compounds are prepared directly from aryl halides in a single reaction vessel by contacting aryl halide with elemental magnesium and a nickel catalyst comprising a nickel compound and a coordinating ligand in an aprotic, non-polar, ether-containing solvent system for a time and under conditions suitable for the formation of biaryl compound.
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Davis Curtis R.
Eastman Kodak Company
Heath, Jr. William P.
Reiter S. E.
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