Preparation of .beta.-lactam derivatives

Details Preparation of .beta.-lactam derivatives Preparation of .beta.-lactam derivatives

1980-06-30

1985-08-20

Berch, Mark L.

Chemistry of carbon compounds

Miscellaneous organic carbon compounds

C-metal

2603303, C07D20508

Patent

active

045363340

ABSTRACT:
A process for preparing a .beta.-lactam derivative having a hydrogen atom on the nitrogen atom of the .beta.-lactam ring, which comprises reacting a .beta.-lactam derivative having a mono- or diarylmethyl group on the nitrogen atom of the .beta.-lactam ring with an acid or ceric ammonium nitrate to cleave the bond between the nitrogen atom and the mono- or diarylmethyl group; and novel .beta.-lactam derivatives useful as intermediates for the synthesis of pharmaceutical agents.

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