Preparation of anhydropolyamino acids at temperatures of 350.deg

Chemistry: natural resins or derivatives; peptides or proteins; – Peptides of 3 to 100 amino acid residues

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528310, 528328, 530324, C08G 6910

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active

054497485

ABSTRACT:
There is disclosed a process for preparing polysuccinimide by thermal condensation of L-aspartic acid to produce polysuccinimide wherein the L-aspartic acid is exposed to an atmosphere in excess of about 350.degree. C. and to a temperature in the range of from about 350.degree. C. to about 400.degree. C. for a period of time of from about 6 to about 15 minutes. Under such conditions, at least about 90% conversion of the L-aspartic acid is provided. The polysuccinimide may be hydrolysed to provide polyaspartic acid by conventional hydrolysis under basic conditions.

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