Preparation of an antibiotic selectively effective against staph

Details Preparation of an antibiotic selectively effective against staph Preparation of an antibiotic selectively effective against staph

1984-02-06

1985-04-23

Shapiro, Lionel M.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Enzymatic production of a protein or polypeptide

435253, 435822, 424115, 260112R, C12P 2100, C12N 120, C12R 101

Patent

active

045130833

ABSTRACT:
A strain (ATCC 31918) of Rothia dentocariosa which, upon fermentation, produces an antibiotic--staphylocidin--which is selectively effective against staphylococci, particularly those with S. aureus and S. epidermidis; and a process for producing such antibiotic by cultivation of the strain under aerobic conditions. Staphylocidin-containing products comprising the cell murein from the fermentation product are also disclosed.

REFERENCES:
Schleifer et al., Bacteriological Reviews, vol. 36 (4), pp. 407-477, (1972).

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