Preparation of .alpha.-L antibody, purification of .alpha.-L ant

Drug – bio-affecting and body treating compositions – Radionuclide or intended radionuclide containing; adjuvant... – Molecular bilayer structure

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252408, 23230B, 424 8, 260112R, A61K 4300, G01N 3316

Patent

active

041327675

ABSTRACT:
Process for the preparation of a novel .alpha.-L antibody comprising immunizing an animal other than a human with the .alpha.-L antigen or .alpha.-L antigen/.alpha.-L antibody complex, and collecting antiserum from the animal; a method for the purification of .alpha.-L antigen comprising subjecting the material containing the .alpha.-L antigen to the density gradient centrifugation, and collecting a fraction having a buoyant density less than 1.1 g/ml; a reagent comprising .alpha.-L antigen; and a reagent comprising .alpha.-L antibody for detection of the .alpha.-L antigen and the .alpha.-L antibody, such detection being useful for the diagnosis of liver diseases and examination of the blood for blood transfusion.

REFERENCES:
patent: 3663684 (1972-05-01), Freedman et al.
patent: 3697638 (1972-10-01), Hansen
patent: 3823126 (1974-07-01), Bjorklund
patent: 3867363 (1975-02-01), Hansen
patent: 3956258 (1976-05-01), Hansen
patent: 3960827 (1976-06-01), Bjorklund

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