Preparation of .alpha.,.beta.-unsaturated ketones

Details Preparation of .alpha.,.beta.-unsaturated ketones Preparation of .alpha.,.beta.-unsaturated ketones

1991-08-05

1995-06-27

Venkat, Jyothsna

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

549 13, 549 78, 549427, 568314, 568346, C07D26108, C07D33502, C07D30904, C07C 4500

Patent

active

054281741

ABSTRACT:
.alpha.,.beta.-Unsaturated ketones of the general formula I ##STR1## where R is an organic radical, are prepared by reacting a corresponding aldehyde R--CHO with acetoacetic acid or one of its salts in the presence of an amine in a two-phase reaction mixture by a process in which the reaction is carried out at a pH of from 6 to 8 in the presence of a catalytic amount of a primary amine.

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"Chem Sources-U.S.A" pp. 61, 49, 491-493 (1984).
Copy and Eundberg, Advanced Organic Chem. vol. A [New York: Plenum Press, 1984] pp. 332, 343.
Morrison and Boyd, Organic Chemistry, (Boston, Allyn and Bacon 1979), pp. 564-565.
European Search Report.
Organikum; Organisch-chemisches Grundpraktikum, pp. 466-468, VEB Deutscher, Berlin (1986).
Csaba Szantay und Janos Rohaly, Uber die Bildung ungesattigter Ketone in den Mannich-Reaktionen substituierter Acetessigsauren, Chem. Ber., v. 96, pp. 1788-1791 (1963).

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