Organic compounds -- part of the class 532-570 series – Organic compounds – Carbohydrates or derivatives
Reexamination Certificate
2006-02-13
2009-10-13
McIntosh, III, Traviss C (Department: 1623)
Organic compounds -- part of the class 532-570 series
Organic compounds
Carbohydrates or derivatives
C536S022100, C536S124000, C549S314000
Reexamination Certificate
active
07601820
ABSTRACT:
The present invention provides (i) a process for preparing a 2-deoxy-2-fluoro-2-methyl-D-ribonolactone derivative, (ii) conversion of the lactone to nucleosides with potent anti-HCV activity, and their analogues, and (iii) a method to prepare the anti-HCV nucleosides containing the 2-deoxy-2-fluoro-2-C-methyl-β-D-ribofuranosyl nucleosides from a preformed, preferably naturally-occurring, nucleoside.
REFERENCES:
patent: 3798209 (1974-03-01), Witkowski et al.
patent: RE29835 (1978-11-01), Witkowski
patent: 4957924 (1990-09-01), Beauchamp
patent: 5026687 (1991-06-01), Yarchoan et al.
patent: 5118820 (1992-06-01), Hertel
patent: 5149794 (1992-09-01), Yatvin et al.
patent: 5157027 (1992-10-01), Biller et al.
patent: 5194654 (1993-03-01), Hostetler et al.
patent: 5223263 (1993-06-01), Hostetler et al.
patent: 5256641 (1993-10-01), Yatvin et al.
patent: 5372808 (1994-12-01), Blatt et al.
patent: 5405598 (1995-04-01), Schinazi et al.
patent: 5411947 (1995-05-01), Hostetler et al.
patent: 5420266 (1995-05-01), Britton et al.
patent: 5462724 (1995-10-01), Schinazi et al.
patent: 5463092 (1995-10-01), Hostetler et al.
patent: 5496546 (1996-03-01), Wang et al.
patent: 5538865 (1996-07-01), Reyes et al.
patent: 5543389 (1996-08-01), Yatvin et al.
patent: 5543390 (1996-08-01), Yatvin et al.
patent: 5543391 (1996-08-01), Yatvin et al.
patent: 5554728 (1996-09-01), Basava et al.
patent: 5610054 (1997-03-01), Draper
patent: 5633358 (1997-05-01), Gruetzke et al.
patent: 5633388 (1997-05-01), Diana et al.
patent: 5676942 (1997-10-01), Testa et al.
patent: 5703058 (1997-12-01), Schinazi et al.
patent: 5711944 (1998-01-01), Gilbert et al.
patent: 5725859 (1998-03-01), Omer
patent: 5738845 (1998-04-01), Imakawa
patent: 5738846 (1998-04-01), Greenwald et al.
patent: 5747646 (1998-05-01), Hakimi et al.
patent: 5767097 (1998-06-01), Tam
patent: 5792834 (1998-08-01), Hakimi et al.
patent: 5830455 (1998-11-01), Valtuena et al.
patent: 5830905 (1998-11-01), Diana et al.
patent: 5834594 (1998-11-01), Hakimi et al.
patent: 5837257 (1998-11-01), Tsai et al.
patent: 5846964 (1998-12-01), Ozeki
patent: 5849696 (1998-12-01), Chretien et al.
patent: 5869253 (1999-02-01), Draper
patent: 5891874 (1999-04-01), Colacino et al.
patent: 5905070 (1999-05-01), Schinazi et al.
patent: 5908621 (1999-06-01), Glue et al.
patent: 5922757 (1999-07-01), Chojkier
patent: 5928636 (1999-07-01), Alber et al.
patent: 5942223 (1999-08-01), Bazer et al.
patent: 5980884 (1999-11-01), Blatt et al.
patent: 5990276 (1999-11-01), Zhang et al.
patent: 6004933 (1999-12-01), Spruce et al.
patent: 6034134 (2000-03-01), Gold et al.
patent: 6043077 (2000-03-01), Barber et al.
patent: 6056961 (2000-05-01), Lavie et al.
patent: 6090932 (2000-07-01), McGee et al.
patent: 6130326 (2000-10-01), Ramasamy et al.
patent: 6156501 (2000-12-01), McGall et al.
patent: 6232300 (2001-05-01), Schinazi et al.
patent: 6239159 (2001-05-01), Brown et al.
patent: 6348587 (2002-02-01), Schinazi et al.
patent: 6391859 (2002-05-01), Schinazi et al.
patent: 6410531 (2002-06-01), Llinas-Brunet et al.
patent: 6420380 (2002-07-01), Llinas-Brunet et al.
patent: 6455513 (2002-09-01), McGuigan et al.
patent: 6455690 (2002-09-01), Tam et al.
patent: 6479463 (2002-11-01), Wang et al.
patent: 6495677 (2002-12-01), Ramasamy et al.
patent: 6509320 (2003-01-01), Wang et al.
patent: 6534523 (2003-03-01), Llinas-Brunet et al.
patent: 6552183 (2003-04-01), Ramasamy et al.
patent: 6555677 (2003-04-01), Petrillo et al.
patent: 6573248 (2003-06-01), Ramasamy et al.
patent: 6642206 (2003-11-01), Ramasamy et al.
patent: 6660721 (2003-12-01), Devos et al.
patent: 6677314 (2004-01-01), Klecker et al.
patent: 6677315 (2004-01-01), Klecker et al.
patent: 6680303 (2004-01-01), Schinazi et al.
patent: 6682715 (2004-01-01), Klecker et al.
patent: 6683045 (2004-01-01), Klecker et al.
patent: 6703374 (2004-03-01), Klecker et al.
patent: 6753309 (2004-06-01), Klecker et al.
patent: 6777395 (2004-08-01), Bhat et al.
patent: 6787305 (2004-09-01), Li et al.
patent: 6787526 (2004-09-01), Bryant et al.
patent: 6815542 (2004-11-01), Hong et al.
patent: 6897201 (2005-05-01), Boyer et al.
patent: 6908924 (2005-06-01), Watanabe et al.
patent: 6914054 (2005-07-01), Sommadossi et al.
patent: 6962991 (2005-11-01), Dempcy et al.
patent: 7018985 (2006-03-01), Boyer et al.
patent: 7018989 (2006-03-01), McGuigan et al.
patent: 7081449 (2006-07-01), Pietrzkowski et al.
patent: 2002/0058635 (2002-05-01), Averett
patent: 2002/0198173 (2002-12-01), Schinazi et al.
patent: 2003/0050229 (2003-03-01), Sommadossi et al.
patent: 2003/0060400 (2003-03-01), LaColla et al.
patent: 2003/0120071 (2003-06-01), McGuigan et al.
patent: 2003/0144502 (2003-07-01), Pietrzkowski et al.
patent: 2003/0153744 (2003-08-01), Mekouar et al.
patent: 2004/0006007 (2004-01-01), Gosselin et al.
patent: 2004/0014108 (2004-01-01), Elarup et al.
patent: 2004/0023240 (2004-02-01), Marliere et al.
patent: 2004/0023901 (2004-02-01), Cook et al.
patent: 2004/0059104 (2004-03-01), Cook et al.
patent: 2004/0063622 (2004-04-01), Sommadassi et al.
patent: 2004/0067901 (2004-04-01), Bhat et al.
patent: 2004/0072788 (2004-04-01), Bhat et al.
patent: 2004/0097461 (2004-05-01), Sommadossi et al.
patent: 2004/0097462 (2004-05-01), Sommadassi et al.
patent: 2004/0101535 (2004-05-01), Sommadossi et al.
patent: 2004/0102414 (2004-05-01), Sommadassi et al.
patent: 2004/0110717 (2004-06-01), Carroll et al.
patent: 2004/0167140 (2004-08-01), Schinazi et al.
patent: 2004/0191824 (2004-09-01), Dempcy et al.
patent: 2004/0214844 (2004-10-01), Otto et al.
patent: 2004/0229839 (2004-11-01), Babu et al.
patent: 2004/0248892 (2004-12-01), Wang
patent: 2004/0254141 (2004-12-01), Schinazi et al.
patent: 2004/0259934 (2004-12-01), Olsen et al.
patent: 2004/0265969 (2004-12-01), Li et al.
patent: 2004/0266996 (2004-12-01), Rabi
patent: 2005/0009737 (2005-01-01), Clark
patent: 2005/0020825 (2005-01-01), Storer et al.
patent: 2005/0026853 (2005-02-01), Mekouar et al.
patent: 2005/0031588 (2005-02-01), Sommadassi et al.
patent: 2005/0075309 (2005-04-01), Storer et al.
patent: 2005/0080034 (2005-04-01), Standring et al.
patent: 2005/0090660 (2005-04-01), Watanabe et al.
patent: 2005/0124532 (2005-06-01), Sommadossi et al.
patent: 2005/0130931 (2005-06-01), Boyer et al.
patent: 2005/0137161 (2005-06-01), Sommadossi et al.
patent: 2005/0148534 (2005-07-01), Castellino et al.
patent: 2005/0164960 (2005-07-01), Olsen et al.
patent: 2005/0215513 (2005-09-01), Boojamra et al.
patent: 2005/0227947 (2005-10-01), Chan et al.
patent: 2005/0261237 (2005-11-01), Boojamra et al.
patent: 2006/0003951 (2006-01-01), Mekouar et al.
patent: 2006/0014943 (2006-01-01), Dempcy et al.
patent: 2006/0035866 (2006-02-01), Cannizzaro et al.
patent: 2006/0040944 (2006-02-01), Gosselin et al.
patent: 2006/0079478 (2006-04-01), Boojamra et al.
patent: 2006/0110727 (2006-05-01), McGall et al.
patent: 2006/0122146 (2006-06-01), Chun et al.
patent: 2006/0122154 (2006-06-01), Olsen et al.
patent: 2006/0142238 (2006-06-01), McGuigan
patent: 2006/0144502 (2006-07-01), Weder
patent: 2007/0087960 (2007-04-01), Storer et al.
patent: 19914474 (1998-03-01), None
patent: 180276 (1984-10-01), None
patent: 350287 (1989-07-01), None
patent: WO8902733 (1989-04-01), None
patent: WO9000555 (1989-06-01), None
patent: WO9116920 (1991-11-01), None
patent: WO9118914 (1991-12-01), None
patent: WO9119721 (1991-12-01), None
patent: WO9300910 (1993-01-01), None
patent: WO9426273 (1994-11-01), None
patent: WO9513090 (1995-05-01), None
patent: WO 95/24185 (1995-09-01), None
patent: WO9615132 (1996-05-01), None
patent: WO 96/32403 (1996-10-01), None
patent: WO9736554 (1997-10-01), None
patent: WO 98/16184 (1998-04-01), None
patent: WO9817679 (1998-04-01), None
patent: WO9822496 (1998-05-01), None
patent: WO9822496 (1998-05-01), None
patent: WO9907734 (1999-02-01), None
patent: WO9907734 (1999-02-01), None
patent: WO9915194 (1999-04-01), None
patent: WO9932139 (1999-07-01), None
patent: WO9932140 (1999-07-01), None
patent: WO9943691 (1999-09-01), None
patent: WO9959621 (1999-11-01), None
patent: WO9964016 (1999-12-01), None
paten
Chun Byoung-Kwon
Du Jinfa
Shi Junxing
Stec Wojciech
Wang Peiyuan
Duane Morris LLP
McIntosh, III Traviss C
Pharmasset, Inc.
LandOfFree
Preparation of alkyl-substituted... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Preparation of alkyl-substituted..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of alkyl-substituted... will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-4053565