Organic compounds -- part of the class 532-570 series – Organic compounds – Nitrogen attached directly or indirectly to the purine ring...
Patent
1988-11-01
1990-05-22
Shah, Mukund J.
Organic compounds -- part of the class 532-570 series
Organic compounds
Nitrogen attached directly or indirectly to the purine ring...
502353, D01J 2320, C07D24102
Patent
active
049279319
ABSTRACT:
A process for preparing alkyl-extended, alcohol-extended or amine-extended piperazines or mixtures thereof comprising contacting a difunctional aliphatic alcohol with a reactant amine, wherein at least one of the aliphatic alcohol or the reactant amine contains a piperazine moiety, in the presence of a catalyst containing a Group VB metal oxide or a Group VB metal phosphate, or mixtures thereof. For example, monoethanolamine reacts with piperazine in the presence of a catalyst of niobic acid supported on hydrated alumina to yield predominantly N-(2-aminoethyl)piperazine. Also, N-hydroxyethylpiperazine reacts with piperazine in the presence of a catalyst of niobium phosphate to yield predominantly 1,2-bis(piperazinyl)ethane.
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Bowman Robert G.
Hartwell George E.
Molzahn David C.
Shah Mukund J.
The Dow Chemical Company
Ward E. C.
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