Preparation of alkoxy methyl ethers

Organic compounds -- part of the class 532-570 series – Organic compounds – Oxygen containing

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568315, 568592, C07C 4114, C07C 4564

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active

045007381

ABSTRACT:
Alkoxymethyl protecting groups for organic hydroxyl substituents may be introduced into the desired compounds by acetal exchange between an alkylal and an alcohol in the presence of phosphorus oxychloride and dimethylformamide.

REFERENCES:
patent: 3928626 (1975-12-01), Yardley et al.
patent: 3987105 (1976-10-01), Yardley
Edwards et al., Jour. Chem. Soc., (1967), 411-413.
Fujii et al., Synthesis, (1975), 276-277.
Yardley et al., Synthesis, (1976), 244.
Olah et al., Synthesis, (1981), 471-472.
Schaper, Synthesis, (1981), 794-796.

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