Chemistry: natural resins or derivatives; peptides or proteins; – Proteins – i.e. – more than 100 amino acid residues – Chemical modification or the reaction product thereof – e.g.,...
Patent
1991-02-28
1994-07-12
Hill, Jr., Robert J.
Chemistry: natural resins or derivatives; peptides or proteins;
Proteins, i.e., more than 100 amino acid residues
Chemical modification or the reaction product thereof, e.g.,...
530405, 530406, 530402, 530350, 4241851, 4242761, A61K 3935, A61K 3702, C07K 1300, C12P 2102
Patent
active
053289919
ABSTRACT:
Proteins, referred to as modified human T cell reactive feline proteins, which have reduced ability to bind immunoglobulin E from cat allergic individuals and substantially unaltered ability to stimulate T cells from cat allergic individuals (relative to affinity purified T cell reactive feline protein) and a method of making such proteins. The modified human T cell reactive feline proteins are useful in desensitization treatment of cat allergic individuals.
REFERENCES:
patent: 4163778 (1979-08-01), Ohman
patent: 4946945 (1990-08-01), Wojdani
Kudo, K., et al. (1976) J. Allergy Clin. Immunol. 61:1-9.
Oka, S. et al. (1987) J. Allergy Clin. Immunol. 80:57-63.
Didierlaurent, A. et al., Int. Archs. Allergy Appl. Immun., vol. 73:27-31 (1984).
Jenkins, M. et al., J. Exp. Med., vol. 165: 302-319 (1987).
DeGroot, H. et al., J. Allergy Clin. Immunol., vol. 82: 778-786 (1988).
Chapman, M. et al., J. Of Immun, vol. 140(3): 812-818 (Feb. 1, 1988).
Duffort, O. et al., Immunology Letters, vol. 17: 71-77 (1988).
Duffort, O. et al., Int. Archs. Allergy appl. Immun., vol. 84: 339-344 (1987).
Sundin, B., et al., J. of Allergy Clin. Immunol.,vol. 77: 478-487 (1986).
Lowenstein, H. et al., Allergy, vol. 40: 430-441 (1985).
Anderson, M. et al., J. Allergy Clin. Immunol., vol. 76: 563-569 (1985).
Ohman, J. et al., J. Allergy Clin. Immunol., vol. 4: 230-239 (1984).
Leitermann, K. et al., J. Allergy Clin. Immunol., vol. 74: 147-153 (1984).
Ohman, J. et al, J. Of Immunology, vol. 113 (6): 1668-1677 (Dec. 1974).
Barnes et al., J. Allergy & Clinical Immunology, vol. 85: 169 (1990).
Lerner, Richard A., "Tapping the immunological repertoire to produce antibodies of predetermined specificity", Nature, vol. 299, Oct. 14, 1982.
Morgenstern, Jay et al., Proc. Natl. Acad. Sci. USA, vol. 88, Nov. 1991, pp. 9690-9694.
Channing Stacey L.
Fitzgerald David L.
Hill Jr. Robert J.
Immulogic Pharmaceutical Corp.
Vanstone Darlene A.
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