Preparation of alkali metal choline salicylate salt complexes

Chemistry of carbon compounds – Miscellaneous organic carbon compounds – C-metal

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C07C 9100

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040988139

ABSTRACT:
Choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds of the formula, ##STR1## WHEREIN Me represents the sodium, potassium or lithium ion and R represents the sulfite, bisulfite, metabisulfite, dithionate, hydrosulfite and hyposulfite groups are described. Said compounds are stable and inhibit the formation of color in pharmaceutical preparations containing the same. The method for the preparation of choline salicylate sulfite and choline salicylate alkali metal sulfite-containing compounds, and pharmaceutical dosage forms containing the same are disclosed together with a method for their use to inhibit color formation.

REFERENCES:
patent: 3069321 (1962-12-01), Kahn et al.
patent: 3855282 (1974-12-01), Kelly et al.
patent: 3947491 (1976-03-01), Kelly et al.
patent: 4001311 (1977-01-01), Kelly et al.

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