Preparation of acylated sucrose derivatives

Details Preparation of acylated sucrose derivatives Preparation of acylated sucrose derivatives

1989-09-26

1992-08-25

Griffin, Ronald W.

Chemistry: molecular biology and microbiology

Micro-organism, tissue cell culture or enzyme using process...

Preparing compound containing saccharide radical

435198, 435 72, 435 74, C12P 1912, C12P 1944

Patent

active

051418606

ABSTRACT:
Sucrose derivatives partially acylated in each ring can be obtained by treating a fully or partially acylated sucrose derivative with an enzyme having sucrose esterase activity capable of removing at least one acyl group from each ring, generally comprising or being a component of a lipase, esterase, amylase, .alpha.-galactosidase or protease preparation, the enzyme treatment being effected in an aqueous system. Sucralose can be obtained by using this method to obtain a sucrose 2,3,6,3',4'-penta ester which can then be chlorinated and de-esterfied. Some of the penta acetates, tetraacetates and mixed acetates/butyrates are new compounds.

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