Chemistry: molecular biology and microbiology – Enzyme – proenzyme; compositions thereof; process for... – Oxidoreductase
Patent
1980-05-09
1982-10-05
Shapiro, Lionel M.
Chemistry: molecular biology and microbiology
Enzyme , proenzyme; compositions thereof; process for...
Oxidoreductase
435 25, 435 26, 435190, 435814, 435822, 435842, C12N 902, C12N 904, C12Q 132
Patent
active
043528856
ABSTRACT:
A partially purified NADP specific thermostable alcohol, aldehyde/ketone oxidoreductase is prepared which can react with a wide range of alcohols, ketones and aldehydes. The enzyme has a unique preference for secondary over primary alcohols. The thermostability, broad range of operating temperatures and lack of sensitivity to metal ions and complexing agents, in addition to the absolute specifity for the coenzyme, increase the utility of the enzyme in asymmetric organic synthesis and NADPH regeneration.
REFERENCES:
patent: 3796635 (1974-03-01), Delente
patent: 4131727 (1978-12-01), Lange et al.
patent: 4250259 (1981-02-01), Hou et al.
Tsai et al., Archives Biochemistry and Biophysics, vol. 199, No. 2, pp. 626-634, 1980.
Hou et al., Applied and Environmental Microbiology, Jul. 1979, pp. 135-142, vol. 38, No. 1.
Patel et al., Eur. J. Biochem. 101, 401-406 (1979).
Barth et al., Zeitschrift fur Allgemeine Mikrobiologie, 19, 381-390 (1979).
Zeikus et al., Enzyme Microb. Technol., vol. 1, pp. 243-252 (Oct. 1979).
Lamed Raphael J.
Zeikus Joseph G.
Shapiro Lionel M.
Wisconsin Alumni Research Foundation
LandOfFree
Preparation of a novel NADP linked alcohol-aldehyde/ketone oxido does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Preparation of a novel NADP linked alcohol-aldehyde/ketone oxido, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of a novel NADP linked alcohol-aldehyde/ketone oxido will most certainly appreciate the feedback.
Profile ID: LFUS-PAI-O-423646