Preparation of a gamma-globulin solution suitable for intravenou

Details Preparation of a gamma-globulin solution suitable for intravenou Preparation of a gamma-globulin solution suitable for intravenou

1976-09-07

1979-05-15

Schain, Howard E.

Drug, bio-affecting and body treating compositions

Fermentate of unknown chemical structure

Having a known elemental analysis

424177, 260112B, A23J 106, C07G 700

Patent

active

041548191

ABSTRACT:
In the preparation of a gamma-globulin solution suitable for the intravenous application by reaction of a solution of standard gamma-globulin with a reagent to combine with the anticomplementary material contained therein and separating the solution from the solids, the improvement which comprises employing as said reagent at least one member selected from the group consisting of acetimido ethyl ester hydrochloride, diketene, propanesultone and formimido ethyl ester hydrochloride.

REFERENCES:
patent: 3916026 (1975-10-01), Stephan
Chem. Abstracts, vol. 75, 1971, 17954k, Stephan.
Noller, 2nd Edition Chemistry of Organic Compounds, 1957, pp. 762, 782 and 824-825.
Chem. Abstracts, vol. 84, 1976, 132339m, Heremans et al., effective date 2/5/76.

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