Preparation of a diagnostic agent for measuring the coagulabilit

Details Preparation of a diagnostic agent for measuring the coagulabilit Preparation of a diagnostic agent for measuring the coagulabilit

1974-11-11

1976-09-28

Naff, David M.

Textiles: fiber preparation

23230B, 1951035R, 424 2, 424105, G01N 3100, G01N 3316, A61K 3548

Patent

active

039830047

ABSTRACT:
A diagnostic agent containing thromboplastin sensitive to factor VII and factor X for measuring the coagulability of blood is prepared by extracting an aqueous suspension of thrombogenic tissue at pH 10 to 12, acidifying the extract, separating the extract from the tissue and adding a water-soluble calcium salt to the extract. The agent can be stabilized by adding to the extract cholanic acid and a water-soluble heavy metal-II-salt.

REFERENCES:
patent: 2687980 (1954-08-01), Blanchard et al.
patent: 2847347 (1958-08-01), Singher et al.
patent: 3522148 (1970-07-01), Adam et al.
patent: 3862314 (1975-01-01), Zwisler et al.

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