Preparation of 8-bromomethyl-3-methylquinoline compounds

Details Preparation of 8-bromomethyl-3-methylquinoline compounds Preparation of 8-bromomethyl-3-methylquinoline compounds

1989-06-05

1990-09-18

Springer, David B.

Chemistry: electrical and wave energy

Processes and products

Processes of treating materials by wave energy

546180, C07D21518, B01J 1912

Patent

active

049576089

ABSTRACT:
A process for the preparation of 8-bromomethyl-3-methylquinoline compounds of the formula I ##STR1## where one or both substituents X are chlorine and, where relevant, the other substituent X is hydrogen, by bromination of the corresponding 8-methylquinoline compound in the presence of a 2-phase mixture of a solvent stable to bromination and of, preferably, buffered water.

REFERENCES:
patent: 4715889 (1987-12-01), Hagen et al.
Chem. Ab. 51,427, vol. 199, No. 7, p. 167 (1984).
Fuson, Advanced Organic Chemistry, 30-35, 288-289, Wiley (1950).

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