Preparation of 7-(3-(propylamino)-2-hydroxypropoxy)flavone

Details Preparation of 7-(3-(propylamino)-2-hydroxypropoxy)flavone Preparation of 7-(3-(propylamino)-2-hydroxypropoxy)flavone

1986-07-18

1988-07-19

Chan, Nicky

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D31130

Patent

active

047586796

ABSTRACT:
In a process for preparing 7-[3-(propylamino)-2-hydroxypropoxy]flavone by the reaction of 7-(2,3-epoxypropoxy)flavone and n-propylamine, the improvement which resides in treating the beta-aminochalcone by-product with a weak organic acid to convert the chalcone to the desired aminated flavone.

REFERENCES:
patent: 3450717 (1969-06-01), Kramer et al.
patent: 3462455 (1969-08-01), Kramer et al.
patent: 3637718 (1972-01-01), Kramer et al.
patent: 3993669 (1976-11-01), Pfister
patent: 4241069 (1980-12-01), Buckler et al.
patent: 4461907 (1984-07-01), Batchelor et al.
patent: 4495198 (1985-01-01), Wu
Indian J. Chem., vol. 13, No. 4, 425, (1975).

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