Preparation of 5-vinylpyrrolidones

Details Preparation of 5-vinylpyrrolidones Preparation of 5-vinylpyrrolidones

1994-06-27

1996-03-05

Springer, David B.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

548543, C07D20726

Patent

active

054969581

ABSTRACT:
A process for the preparation of a 5-vinylpyrrolidone of the formula ##STR1## wherein each of R.sup.1 and R.sup.2 is hydrogen or alkyl and R.sup.3 is preferably hydrogen but may further represent alkyl, cycloalkyl, aryl, alkylaryl, arylalkyl or a 5- to 6-membered aromatic or non-aromatic heterocyclic group containing 1 to 3 nitrogen atoms and/or an oxygen or sulfur atom, the process being carried out in two steps, first to react a 3-formylpropionic acid ester of the formula ##STR2## where each of R.sup.1 and R.sup.2 is hydrogen or C.sub.1 -C.sub.8 -alkyl, and R.sup.4 is hydrogen, alkyl, cycloalkyl, aryl, alkylaryl or arylalkyl, with a vinylymagnesium halide of the formula

REFERENCES:
patent: 3775431 (1973-11-01), Rodewald, Jr.
patent: 5286875 (1994-02-01), Fischer
Janowitz et al, Synlett, No. 1 (1989) pp. 24-25.
Zalinyan et al, " . . . Stereoselective synthesis of .nu.-lactones," Chem. Abstracts, vol. 75, No. 3, 20181m (1971).

Affiliated with

Also associated with

Rating

Preparation of 5-vinylpyrrolidones does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Preparation of 5-vinylpyrrolidones, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Preparation of 5-vinylpyrrolidones will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFUS-PAI-O-1414235