Preparation of 5,6,7,7a-tetrahydro-4H-thieno[3,2-c]pyridin-2-one

Details Preparation of 5,6,7,7a-tetrahydro-4H-thieno[3,2-c]pyridin-2-one Preparation of 5,6,7,7a-tetrahydro-4H-thieno[3,2-c]pyridin-2-one

1984-07-25

1985-05-07

Ramsuer, Robert W.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D49504

Patent

active

045159513

ABSTRACT:
The present invention provides derivatives of 5,6,7,7a-tetrahydro-4H-thieno[3,2-c]pyridin-2-one of the general formula: ##STR1## in which R is a hydrogen atom or a phenyl radical, which is optionally substituted by at least one halogen atom or lower alkyl radical, lower alkoxy radical, nitro group, carboxyl group, alkoxycarbonyl radical or cyano group, R' is a hydrogen atom or a lower alkyl radical and n is 0, 1, 2, 3, or 4; and the addition salts thereof with pharmaceutically acceptable mineral or organic acids.
The present invention also provides a process for the preparation of these compounds, as well as pharmaceutical compositions containing them.

REFERENCES:
patent: 4097482 (1978-06-01), Amselem
patent: 4424356 (1984-01-01), Maffrand et al.
patent: 4458074 (1984-07-01), Bouscuet et al.
Elguero et al., The Tautomerism of Heterocycles, Supplement 1, (1976), p. 229.

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