Preparation of 4-substituted pyridines using quaternary pyridine

Details Preparation of 4-substituted pyridines using quaternary pyridine Preparation of 4-substituted pyridines using quaternary pyridine

1985-01-16

1987-06-09

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

546301, 546304, 546306, 546311, 546312, C07B 4102, C07B 4304, C07B 4104, C07D21374

Patent

active

046721215

ABSTRACT:
A process for preparing a 4-substituted pyridine product from a starting pyridine substituted in the 4-position by a leaving group susceptible to nucleophilic displacement when the starting pyridine is in quaternized form, comprises,

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patent: 3689470 (1972-09-01), Shachat et al.
patent: 4158093 (1979-06-01), Bailey et al.
patent: 4220785 (1980-09-01), Oude Alink et al.
Turner, S. "The Design of Organic Syntheses" (1976) Elsevier Scientific Publishing Co., pp. 149-165.
Dowbenko, J. Org. Chem., 25, 1123 (1960).

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