Preparation of 4-nitro-5-imidazolyl ethers and thioethers

Details Preparation of 4-nitro-5-imidazolyl ethers and thioethers Preparation of 4-nitro-5-imidazolyl ethers and thioethers

1988-06-01

1990-02-13

Lee, Mary C.

Organic compounds -- part of the class 532-570 series

Organic compounds

Chalcogen bonded directly to ring carbon of the purine ring...

544327, 544331, 544328, 546177, 546210, 546278, 548197, 548214, 548338, 548339, 548340, 548336, C07D27900, C07D40100, C07D26104, C07D41700

Patent

active

049008250

ABSTRACT:
4-Nitro-5-imidazolyl ethers and thioethers of the formula I ##STR1## where R.sup.1 is alkyl, alkoxyalkyl, cycloalkyl, aryl, aralkyl or alkylaryl, R.sup.2 is hydrogen, alkyl, cycloalkyl, aryl, aralkyl or alkylaryl, R.sup.3 is alkyl, cycloalkyl, aryl, aralkyl, alkylaryl or a heterocyclic or heteroaromatic radical or a counter-ion of the corresponding alcoholate or thiolate or, where X is sulfur, R.sup.3 is hydrogen, and X is oxygen or sulfur, and the stated organic radicals may furthermore carry substituents which are inert under the reaction conditions, are prepared by reacting a dinitroimidazole of the formula II ##STR2## with an alcohol or thiol of the formula III

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