Preparation of 4-methylimidazoles

Details Preparation of 4-methylimidazoles Preparation of 4-methylimidazoles

1981-04-13

1983-03-22

Jiles, Henry R.

Organic compounds -- part of the class 532-570 series

Organic compounds

Heterocyclic carbon compounds containing a hetero ring...

C07D23358

Patent

active

043776965

ABSTRACT:
A process for the preparation of 4-methylimidazoles by reacting methylglyoxal with ammonia and an aldehyde in aqueous solution, wherein the reaction is carried out at a pH of above 7 and either the reactants are all brought into contact simultaneously or the aldehyde and the methylglyoxal are added simultaneously to the aqueous ammonia solution.

REFERENCES:
patent: 3715365 (1973-02-01), Schulze
patent: 4074054 (1978-02-01), Christidis et al.
Sasaki, Chem. Abst. 1959, vol. 53, p. 11392a.

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